Ventriculography Modality in Detection and Evaluation of Cardiotoxicity in Breast Cancer Patients Receiving Chemotherapy: A Literature Review

Background: Ventriculography or Multigated Acquisition Scanning (MUGA) has been the gold standard for baseline and serial assessment of Left Ventricular Ejection Fraction (LVEF) cardiotoxicity since 1970. However, several modalities have proposed to substitute Ventriculography. This study aimed find out whether can still be considered monitor detect before, during, after administration chemotherapy compare with Cardiac Magnetic Resonance (CMR) Echocardiography (Echo).Methods: A literature review was done by searching original keyword combinations on PubMed, Cochrane, ClinicalKey in past five years (2016–2021) language restrictions only English. Of 1,381 pieces literature, are included this study. Results: high sensitivity specificity monitoring detecting cardiotoxicity. Other CMR Echo. is more accurate although it costly whilst Echo interobserver variability. not shown interchangeable results. The also shows that could evaluate assessing diastolic function. Conclusions: used as cardiac function at an affordable price acceptable side effects. It recommends choosing one modality due results among